Adult polyglucosan body disease (APBD) is a condition that affects the nervous system. People with APBD typically first experience signs and symptoms related to the condition between ages 35 and Initial symptoms of the disorder include numbness and tingling in the legs (peripheral neuropathy) and progressive muscle weakness and stiffness (spasticity). 2 days ago · Autosomal dominant polycystic kidney disease is an important cause of renal failure. It is inherited as an autosomal dominant trait with penetrance approaching % in those surviving until their seventh or eighth decade. The condition most usually presents in adult life but may develop at any time, including in utero.
Jun 03, · Polycystic kidney disease (PKD) is an inherited kidney disorder. It causes fluid-filled cysts to form in the kidneys. PKD may impair kidney function .